1 a point on a trail, waterway, etc. where the route changes in nature or direction, marking a new leg of the journey.
See also: leavings
2a Esp. North a place, usually a town, where one leaves the railway or other link with civilization to proceed into the wilderness.
See also: jumping-off point (def. 1) jumping-off spot jumping-off town jump-off point kicking-off place
2b any starting place.
See also: jumping-off point (def. 2)
3 † any place considered the ultimate in isolated, undeveloped wilderness.